Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template ; Functional Keywords, dna ...
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Persistent thymine dimers are thought to hinder DNA transcription and replication by stalling the progress of RNA polymerase (20,21). This can cause cellular ...
Missing: Transport | Show results with:Transport
Binary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template ; Total number of polymer chains, 4 ; Total ...
Feb 24, 2011 · Human DNA polymerase κ (Polκ), a member of the Y-family of DNA polymerases, is unable to insert nucleotides opposite the 3'T of a cis-syn T-T ...
Missing: Transport | Show results with:Transport
This error-prone DNA polymerase causes nucleotide synthesis to occur opposite the thymine dimers, with a low degree of fidelity. This leads to high frequencies ...
Though polη's active site is known to be rigid with few conformational changes, there are several contributing factors that could facilitate the lesion bypass ...
Jul 6, 2004 · Ternary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template and an incoming ...
Feb 23, 2007 · Humans have four Y family polymerases—Pol η, Pol ι, Pol κ, and Rev1—each with a unique DNA-damage bypass and fidelity profile. ... In all, Y ...
Feb 13, 1990 · Cis-syn thymine dimers are not absolute blocks to replication by DNA polymerase I of Escherichia coli in vitro · Article Views · Altmetric.
Here, we show that polι is able to facilitate limited translesion replication of a thymine–thymine cyclobutane pyrimidine dimer (CPD). More importantly, however ...